Product Name
HSP70/HSC70 | Heat shock protein 70/Heat shock cognate protein 70 (serum)
Immunogen
KLH-conjugated synthetic peptide conserved across all known sequences of HSP70 P08107 and HSC70 proteins P11142.
Background
Heat shock protein 70 (Hsp70) is the major stress-inducible protein in vertebrates and is highly conserved throughout evolution. It plays a role as a molecular chaperone and is important for allowing cells to cope with acute stress or insult, especially those affecting the protein machinery. Heat shock cognate protein 70 (HSC70) is a highly conserved protein and a member of the family of molecular chaperones. Alternative names: HSP70.1, HSP70-1/HSP70-2, Heat shock 70 kDa protein 8
Purity
Total IgG. Protein G purified in PBS pH 7.4.
Reactivity
Global antibody for HSP70 and HSC70 in fish, mammals and fungi
Confirmed reactivity
Fish, mammals, fungi: Antrodia infirma, A. sinuosa, A. xantha, Catostomus commersonii, Gloeophyllum protractum, Gloeophyllum sepiarium, G. carbonarium, Junghunia luteoalba, Oligoporus sericiomollis, Phlebia cornea
Predicted reactivity
Bovine, Drosophila melanogaster, Hen, Mouse, Rat
Not reactive in
No confirmed exceptions from predicted reactivity are currently known
Reconstitution
For reconstitution add 100 µl of sterile water
Expected/apparent MW
70 kDa
Tested applications
Immunoprecipitation (IP), Western blot (WB)
Recommended dilution
1 : 1000 (IP), 1 : 1000-1: 5000 (WB)
Storage
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.