Analysis of Nematode Feeding Processes

The pathogenic process of plant nematodes is a game between nematodes' pathogenicity and host plant resistance. In this process, nematodes overcome host resistance, colonize, and spread successfully in the tree, and eventually cause the host to wither and die. In conclusion, the nematode overcomes the host plant cell wall and chemical defenses such as reactive oxygen species and terpenes. At the same time interferes with host defenses through functional factors, resulting in host wilt and death.

Lifeasible, as a leading global company, is committed to helping our customers achieve effective and successful research. We provide mechanism analysis of nematode feeding processes. We always deliver reliable results and reports on time to our customers worldwide.

Mechanism Analysis of Nematodes Overcoming Host Physical Barrier

• Host cell wall is the main obstacle to the invasion and feeding of pine wood nematode. To successfully invade the host, nematodes secrete cell wall degradation enzymes to destroy the plant cell wall and overcome the host’s physical barrier.

Fig.1 Processes for nematode feeding on tobacco root hair.

• Lifeasible provides mechanism analysis of nematodes overcoming host physical barrier, mainly including cell wall degrading enzymes and dilating proteases, such as cellulase, glycosyl hydrolase, pectate lyases, expansin, α-L-glycosidase, etc.

Mechanism Analysis of Nematodes Eliminating Host Chemical Defense

• After nematode invasion, the host produces many reactive oxygen species and terpenes to resist or inhibit the invasion of pine wood nematode.
• To colonize the host successfully, nematodes must degrade or eliminate these chemical defense products through detoxification. Therefore, many detoxification genes, including active oxygen scavenging genes and terpene-related detoxification pathway genes, are up-regulated in the pathogenic process of pine wood nematodes.
• We provide mechanism analysis of nematodes eliminating host chemical defense, including removing reactive oxygen species, degrading, and metabolizing terpenes, and others.

Mechanism Analysis of Nematode Regulating Host Defense Responses

• During the interaction between nematodes and hosts, functional factors are secreted to regulate host defense response, induce the accumulation of host defense products, and eventually lead to host death due to excessive defense.
• Different functional factors secreted by nematode affect host's secondary defense response and then cause host death due to excessive defense. We provide mechanism analysis of nematode regulating host defense responses, including venom allergen proteins (VAPs), thaumatin-like proteins (TLPs), cysteine protease inhibitors (CPIs), and other functional factors.

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