Analysis of Nematicide Inhibition of Lipid Synthesis

Lipid synthesis is an important process in most organisms and plant nematodes. Lipid metabolism in nematodes is essential because lipids not only serve for storing and releasing energy but also form important constituents of cell membranes.

Lifeasible develops an advanced platform that provides services to customers worldwide covering analysis for nematicide inhibition of lipid synthesis. ​We customize featured services according to customer needs with decades of experience in plants. In addition, we deliver satisfactory and reliable results and reports on time to our customers worldwide.

Analysis of Acetyl Coenzyme A Carboxylase Inhibitor

• Acetyl coenzyme A carboxylases (ACCs) have crucial roles in fatty acid metabolism in many living organisms; they catalyze the ATP-dependent carboxylation of acetyl-CoA to form malonyl-CoA, which is the first committed step in fatty acid biosynthesis and is the rate-limiting reaction for the pathway.
• By inhibiting the activity of acetyl CoA carboxylase in the process of lipid synthesis in the pest, nematicides disrupt lipid synthesis and block the normal energy metabolism of the pest, ultimately leading to its death.

Fig.1 Chemical control for inhibition of lipid synthesis in plant nematodes.

• Lifeasible provides analysis of acetyl coenzyme A carboxylase inhibitors; the existing examples of registered pesticides are spirotetramat. Our mechanism analysis lists include plant nematode culture, hatching assays, staged developmental assays, infection assays, enzyme assays with radiolabeled sodium bicarbonate, etc.
• With the widespread use of nematicides, plant nematodes may exhibit varying resistance to the drug． We also provide an analysis of drug resistance, including resistance monitoring, the occurrence of cross-resistance, and the resistance mechanism.

Lifeasible offers professional services covering analysis for nematicide inhibition of lipid synthesis to meet your research needs. With years of experience in plants, our advanced platforms can help our clients solve various difficulties and conduct research. If you are interested in our services or have any questions, please feel free to contact us or make an online inquiry.