Development of Bacillus thuringiensis Insecticidal Protein

Bacillus thuringiensis (Bt) insecticide is currently the most widely used in the world, the largest area of use of a class of microbial insecticides. However, due to the existence of Bt insecticidal spectrum is relatively narrow, can only be effective for one or several pests, and some pests have resistance to Bt, limiting the application of Bt promotion. Therefore, it is essential to develop Bt insecticidal proteins to improve Bt insecticidal virulence while avoiding the development of pest resistance.

Lifeasible is an industry-leading biotechnology company dedicated to providing comprehensive solutions for developing customized insecticidal proteins. We develop environmentally friendly biopesticides that are important in protecting the environment and promoting sustainable agricultural development.

Significance of Bacillus thuringiensis (Bt) insecticidal protein development

We isolated the gene to produce Bt insecticidal proteins and inserted it into various crops, such as cotton, corn, and soybean, so that it can produce insecticidal proteins in plant tissues. When ingested by the target pest, these Insecticidal Crystal Proteins (ICPs) are degraded in the digestive tract into small molecules with insecticidal activity Bt insecticidal proteins are widely used in agriculture and are an environmentally friendly alternative to chemical insecticides. The development and use of Bt insecticidal protein can effectively reduce the use of chemical insecticides and promote the sustainable development of agriculture.

What do we offer?

• Genetic engineering. We use genetic engineering techniques by introducing genes encoding, for instance, Bt insecticidal proteins into plant genomes; we can employ genetic engineering techniques to create transgenic crops resistant to insect pests.
• Protein engineering. We change the structure and function of Bt insecticide proteins using protein engineering methods, which can significantly increase the potency, specificity, and stability of Bt insecticide proteins.
• RNA interference. RNA interference technology plays a vital role in biopesticide development. We offer RNA interference technology that, by silencing target genes, decreases pest survival and reproduction. Bt insecticidal proteins can be significantly improved by using the RNA interference technology we offer in their creation.

Advantages of our services

Lifeasible specializes in the development of insecticides and insecticidal proteins and aims to provide a variety of effective solutions to promote sustainable agriculture. With our advanced technology platform and professional technical team, we continue to provide various technical services and products for a wide range of agriculture-related fields. If you are interested in us, please feel free to contact us.