Using Moss to Produce Vaccines and Cosmetics

Over the past few decades, mosses have evolved from obscure plants to model organisms in basic biology, biotechnology, and synthetic biology biotechnology has evolved. Mosses can be grown in stand-alone photobioreactor systems, and a number of key technologies have been implemented in moss systems, including extensive histological techniques, precise genome engineering through homologous recombination with efficiencies similar to those found in yeast, etc. Lifeasible uses moss as a green cell factory for production and has now enabled the production of a relatively large number of compounds with high economic value.

Mosses can be widely used in the production of high-value compounds

Moss has enabled the production of several high-value compounds, such as terpenoids, biopharmaceuticals, and cosmetics. We offer an effective solution for using moss as a green cell factory to produce vaccines and cosmetics.

• Production of vaccines

With the completion of whole genome sequencing, precise genome engineering of mosses can be achieved through homologous recombination (knockout mosses). We use advanced biotechnology to provide an effective solution for moss-based vaccine production. Moss can be widely used in drug products due to the advantages of producing biological drugs, such as the availability of standardized conditions for culture in bioreactors, not being part of the food chain, high biosafety, availability of efficient transformation methods, providing genetic stability and uniform expression of haploids, and fully sequenced genomes. Thus we can use moss as a green cell factory for the production of vaccines for oral vaccines or other vaccine candidates. This solution of ours plays an important role in advancing the field of plant vaccine development.

• Production of cosmetics

Mosses have been widely used in the production of cosmetics. For example, we expressed patchouli alcohol synthase and α/β-santalene synthase in moss to produce two sesquiterpenoids, patchouli alcohol, and α/β-santalol, which are widely used in fragrances, for perfume production. In addition, since Amazon moss can form protective chemical and metabolic strategies against UV damage by biosynthesizing secondary metabolites (e.g., flavonoids), we can use them for the production of sunscreen cosmetics, etc., based on the anabolic characteristics of Amazon moss.

Advantages of our services

Lifeasible is dedicated to agricultural synthetic biology research. We can perform not only base-specific genome editing and create fusion proteins in the original genomic environment of mosses but also down-regulate gene expression using artificial microRNA technology and use the CRISPR/Cas9 system for moss gene editing. We provide advanced technical support and effective solutions in the construction of green cell factories for producing compounds with the high economic value from moss. Efficient and professional is our constant service heart. If you are interested in us, please feel free to contact us, and we look forward to cooperating with you sincerely.